Table 1.
Variable | SLNB Alone (n = 600)
|
SLNB/ALND (n = 336)
|
P | ||||||
---|---|---|---|---|---|---|---|---|---|
No. | % | Median | Range | No. | % | Median | Range | ||
Age at time of axillary surgery, years | 56 | 24-83 | 52 | 27-86 | < .0001 | ||||
Age at follow-up, years | 62 | 28-90 | 56 | 31-89 | < .0001 | ||||
Follow-up, years | 5.0 | 2.7-8.0 | 5.1 | 2.7-7.8 | .41 | ||||
Laterality of surgery | .15 | ||||||||
Right | 310 | 52 | 157 | 47 | |||||
Left | 290 | 48 | 179 | 53 | |||||
Type of surgery | < .0001 | ||||||||
Conservation | 438 | 73 | 157 | 47 | |||||
Mastectomy | 162 | 27 | 179 | 53 | |||||
Tumor type | < .0001 | ||||||||
IFDC | 420 | 70 | 296 | 88 | |||||
IFLC | 47 | 7.8 | 27 | 8.0 | |||||
Mucinous/papillary/medullary/tubular | 23 | 3.8 | 1 | 0.3 | |||||
DCIS only | 79 | 13 | 8 | 2.4 | |||||
DCIS with microinvasion | 22 | 3.7 | 1 | 0.3 | |||||
Metaplastic | 2 | 0.3 | 0 | — | |||||
Other | 7 | 1.2 | 3 | 0.9 | |||||
Pathological size, cm | 1.0 | 0-5.0 | 1.7 | 0-7.5 | < .0001 | ||||
AJCC T stage | |||||||||
Tis | 79 | 13 | 8 | 2.4 | |||||
T1a | 101 | 17 | 15 | 4.5 | |||||
T1b | 158 | 26 | 52 | 15 | |||||
T1c | 212 | 35 | 133 | 40 | |||||
T2 | 50 | 8.3 | 118 | 34. | |||||
T3 | 0 | — | 10 | 3.0 | |||||
Total No. nodes excised | 3 | 1-17 | 19 | 2-65 | < .0001 | ||||
No. of positive nodes | 0 | 0-3 | 1 | 0-32 | < .0001 | ||||
AJCC N stage | |||||||||
N0 | 555 | 93 | 35 | 10 | |||||
N0(i+) | 16 | 2.7 | 9 | 3.6 | |||||
N1mi | 18 | 3.0 | 34 | 9.2 | |||||
N1, 1-3 node(s) positive | 11 | 1.8 | 186 | 55 | |||||
N2, 4-9 nodes positive | 0 | — | 50 | 15 | |||||
N3, ≥10 nodes positive | 0 | — | 22 | 6.5 |
Abbreviations: SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection; IFDC, infiltrating ductal carcinoma; IFLC, infiltrating lobular carcinoma; DCIS, ductal carcinoma in situ; AJCC, American Joint Commission on Cancer.