Table 1. Evolution of resistance mutation profile of child P50, detected by standard genotyping.

Age	Treatment History	Standard Genotyping*
2 yrs 8 months	HIV diagnosis
3 yrs	No ARV	K101E
3 yrs 3 months	AZT+DDI
3 years 4 months	AZT+3TC+NFV
3 yrs 5 months	AZT+3TC+NFV	K101E, G190A, T215F
4 years 5 months	AZT+3TC+NFV	M41L, D67N, T69N, K70R, K101E, M184V, G190A, T215F , K219E

^*Only major drug resistance mutations are listed.

ARV = antiretrovirals, AZT = zidovudine, DDI = didanosine, 3TC = lamivudine, NFV = nelfinavir.