Skip to main content
. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Mamm Genome. 2009 Jan 9;20(2):109–123. doi: 10.1007/s00335-008-9163-4

Figure 1. High resolution meiotic linkage (A) and linkage disequilibrium (B) maps of the rcd2 interval on canine chromosome 7.

Figure 1

A. The map order of 9 microsatellites is indicated with their sequence locations in the CanFam2 assembly of the canine genome. For microsatellites FH2226, CPH20, FH3972 and VIASD10 the number of recombination events observed, between each marker and rcd2, per total number of informative individuals analyzed (126), is listed in parentheses below each marker’s name. SYT14, SERTAD4, KCNH1 and rcd2ms6 all cosegregated with each other, sharing 1 observed recombination with rcd2. Marker rcd2ms3 cosegregated with rcd2 with no observed recombinations.

B. CanFam2 locations and identifying names are listed for 38 SNPs identified in the rcd2 candidate region, as are genotypes for these SNPs from 4 rcd2-affected pedigreed collie dogs (I–IV). Shaded regions indicate where all 4 dogs share identical SNP genotypes. The region encompassed by the dashed box indicates the final rcd2 zero-recombination interval defined by the locations of markers rcd2ms6 and FH3972. The region boxed with a solid outline indicates the minimal region of absolute common LD, defined by the locations of SNP196 and SNP239. The final rcd2 candidate region, representing the overlap of the zero-recombination and absolute common LD intervals is indicated by SNP genotypes in bold.