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. Author manuscript; available in PMC: 2010 Feb 4.
Published in final edited form as: J Am Chem Soc. 2009 Feb 4;131(4):1550–1556. doi: 10.1021/ja8082818

Figure 7.

Figure 7

Structural alignment comparing residues obtained from the decomposition analysis in ε 186–HOT (light blue) superposed with the exonuclease domain (red) of TREX1 (red). Residues from energy decomposition for ε 186–HOT are shown in green; structurally homologous residues for TREX1 are shown in yellow. Metal binding residues (and H162) for ε 186–HOT are shown in light blue; structurally homologous residues for TREX1 are shown in red.