Figure 2. Effect of TNBS-induced colitis on the response to colorectal distension.

Effect of TNBS-induced colitis on the response to CRD of all single pelvic afferent neurons identified (A), on pelvic afferent neurons with a low threshold response (B) or a high threshold response (C), and with low conduction velocity (C-fibres, D) or high conduction velocity (Aδ-fibres, E). Results are expressed as spike rate (Hz). *P < 0.05, **P < 0.01, ***P < 0.001, significantly different from controls, two-way ANOVA with post hoc Student–Newman–Keuls test.