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(A) Four clusters of breakpoints at 1p13.1-21.1, 3p14.1-p14.2, 17q22-q24.3, and 20q12-q13.33. (B) Low copy repeat (LCR) association with clustered and dispersed breakpoints. (C) The four clusters of breakpoints correspond exactly to the four highly amplified regions in MCF-7, as determined by array CGH.
