TABLE 5.
New nomenclature for APH(2″) enzymes
Kan, kanamycin A; Gen, gentamicin; Tob, tobramycin; Net, netilmicin; Dbk, dibekacin; Sis, sisomicin; Ise, isepamicin; Amk, amikacin; Neo, neomycin B; Par, paromomycin; Liv, lividomycin A; Rib, ribostamycin; But, butirosin; Arb, arbekacin.
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Substrate profile
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NTP substrate
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Old nomenclature
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New nomenclature
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|---|---|---|---|---|---|
| Enzyme name | Gene name | Enzyme name | Gene name | ||
| Kan, Gen, Tob, Net, Dbk, Sis, Ise, Amk, Neo, Par, Liv, Rib, But | GTP | APH(2″)-Ia | aph(2″)-Ia | APH(2″)-Ia | aph(2″)-Ia |
| Kan, Gen, Tob, Net, Dbk, Sis, Ise, Amk, Arb, | ATP | APH(2″)-Ib | aph(2″)-Ib | APH(2″)-IIa | aph(2″)-IIa |
| Kan, Gen, Tob, Net, Dbk, Sis | GTP | APH(2″)-Ic | aph(2″)-Ic | APH(2″)-IIIa | aph(2″)-IIIa |
| Kan, Gen, Tob, Net, Dbk, Sis, Ise, Amk, Arb, | ATP/GTP | APH(2″)-Id | aph(2″)-Id | APH(2″)-IVa | aph(2″)-IVa |