FIGURE 4.
Alignment of heterodimeric SDH2 sequences. Amino acid residues proposed for binding of the iron-sulfur clusters are shown in red and those for the quinone binding in blue. Residue numbers refer to the E. coli SDH2 (SdhB) sequence. GenBank™ accession numbers for SDH2N and SDH2C sequences used are T. cruzi (XP_814994 and XP_803796), T. brucei (XP_847169 and XP_826981), and L. major (XP_001683488 and XP_001682013). Other SDH2 sequences used are E. coli (NP_415252), Rickettsia prowazekii (Q9ZEA1), Reclinomonas americana (NP_044798), Dictyostelium discoideum (XP_646559), Plasmodium falciparum (D86574), Tetrahymena thermophila (XP_001024894), S. cerevisiae (NP_012774), Caenorhabditis elegans (NP_495992), H. sapiens (NP_002991), and A. thaliana (NP_189374).