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Repeat 15 has a unique hydrophobic core near Arg1820. Most spectrin repeats have a characteristic tryptophan at position 17 of the A-helix that forms part of the hydrophobic core as exemplified in repeat 14 by Trp1713 (A). In repeat 15, Arg1820 resides at position 17, and the hydrophobic core is centered on Leu1856 from helix-15B (B).
