TABLE 1.

Summary of the experimental data collected for the various CLIP-170 fragments

The affinity of each CLIP-170 fragment for taxol-MTs was measured by cosedimentation assay. Data are the average of three independent experiments. Values are ±S.D. The light scattering entries are a qualitative representation of the data presented in Fig. 3. The microscopy, tip tracking, and lattice binding entries are summaries of the images shown in Figs. 2 and 4 and supplemental Figs. 1 and 2, with data for some fragments not shown. Results are qualitatively summarized by the following symbols: ++, strong positive effect; +, moderate positive effect; +/–, borderline detectable positive effect; –, no effect detected.