Figure 5. GAL4-REV-ERBα (A) and GAL4-REV-ERBβ (B)-Mediated Repression Is Augmented by Co-transfection with Equimolar Amounts (370 fmol/well) of Full-Length NCOR or RIP140 Co-repressors.

Repression, in all cases, is significantly relieved by the addition of Deta/NO. The averages from triplicate experiments are presented as relative luciferase activity.