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. Author manuscript; available in PMC: 2009 Mar 6.
Published in final edited form as: Nat Neurosci. 2005 Jul 17;8(8):1013–1021. doi: 10.1038/nn1505

Figure 5. EphA overexpression causes ipsilateral eye axons to misproject into opposite eye territory.

Figure 5

(a–c) Ipsilateral eye inputs to the P10 LGN of (a) a control-electroporated ferret, (b) a ferret monocularly electroporated with EphA3 and (c) a ferret binocularly electroporated with EphA5. (d–f) In a P10 ferret that was binocularly electroporated with EphA5 on P1, (d) contralateral eye axons, (e) ipsilateral eye axons and (f) their merged representation. Ipsilateral eye expansion into contralateral eye territory was observed here and in every EphA-electroporated ferret examined (n = 16 ferrets). Horizontal plane is shown. Scale bars, 100 µm. Boxed areas (in schematics at right) indicate the site in the LGN where the photomicrographs were taken.