Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PARP-1 is the predominant protein labeled in the PARIS assay. Autoradiographic visualization of SDS/PAGE resolution of PARIS-labeled protein from WT mouse brain sections demonstrates that all signal migrates at approximately 110 kDa, identical to PARP-1 migration. Labeling is abolished by DPQ (10 μM). Specificity of the PARIS assay is further ensured through demonstration that protein labeling is absent in PARP-1−/− brain tissue.
