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Increased serum levels of anti-ssDNA antibody in CIA of D/J.gp130F759 mice. Values are expressed as mean ± standard error of 7 to 10 animals of collagen-immunized mice on day 56 (a) and 3 to 4 animals of non-immunized mice (b). *P < 0.05, **P < 0.01 versus wild-type mice by Student's t-test.
