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Histopathological analysis of gp130F759 mice (12 months) Female
| C57BL/6 | DBA/1J | |||
| Findings | Wild | F759 | Wild | F759 |
| Joint (lower extremity); Synovial cell proliferation | 0/5 | 5/5 | 2/5 | 0/5 |
| Kidney; Glomerulonephritis | 0/5 | 2/5 | 0/5 | 0/5 |
| Eye; Keratitis | 0/5 | 1/5 | 0/5 | 3/5 |
| Lung; Cellular infiltration | 3/5 | 3/5 | 1/5 | 1/5 |
| Spleen; Hyperplasia, plasma cell | 0/5 | 5/5 | 0/5 | 0/5 |
| Thymus; Hypertrophy/hyperplasia, medulla | 0/5 | 5/5 | 0/5 | 4/5 |
| Lymph node (mesenteric); Hyperplasia, plasma cell | 2/5 | 5/5 | 0/5 | 0/5 |
