Table 3.
Destructive arthritis developed in CIA in DBA/1J gp130F759 mice
| Day 56 | Male | Female | |||
| Wlid | F759 | Wild | F759 | ||
| Grade | 20* | 16* | 20* | 14* | |
| Proliferation of the synovial lining cells | 0 | 7 | 0 | 8 | 1 |
| 1 | 1 | 1 | 4 | 0 | |
| 2 | 3 | 3 | 2 | 1 | |
| 3 | 7 | 10 | 4 | 11 | |
| 4 | 2 | 2 | 2 | 1 | |
| Destruction of the articular cartilage/bone | 0 | 9 | 3 | 14 | 1 |
| 1 | 0 | 0 | 1 | 0 | |
| 2 | 4 | 0 | 2 | 0 | |
| 3 | 7 | 8 | 2 | 13 | |
| 4 | 0 | 5 | 1 | 0 | |
| Inflammatory cell infiltration, rich in neutrophils | 0 | 10 | 3 | 12 | 1 |
| 1 | 1 | 0 | 2 | 1 | |
| 2 | 1 | 11 | 2 | 6 | |
| 3 | 5 | 2 | 3 | 5 | |
| 4 | 3 | 0 | 1 | 1 | |
All data refer to the number of limbs with the finding in the group.
*Total number of limbs in the group
Grade of change: 0, negative; 1, very slight; 2, slight; 3, moderate; 4, severe.