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. 2009 Jan 15;9:10. doi: 10.1186/1471-2180-9-10

Table 4.

Rifampin resistance of M. tuberculosis recombinant clones

MIC of rifampin (μg/ml) of M. tuberculosis recombinant clones carrying mutated rpoB gene controlled by:
mutated amino acid of RpoB PrpoB Phsp65

H37Ra KL1936 KL463 H37Ra
H526D 50 50 50 50
D516V 25 25 25 25
Q510H; D516Y 1,5 6,2 6,2 6,2
S512I; D516G 6,2 6,2 6,2 6,2
Q513L 6,2 12,5 50 6,2
M515I; D516Y 6,2 6,2 6,2 6,2
D516Y 3,1 6,2 3,1 6,2
S531L 50 50 50 50
HHS Vulnerability Disclosure