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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Dev Cell. 2009 Jan;16(1):35–46. doi: 10.1016/j.devcel.2008.12.002

Figure 4.

Figure 4

Localization of the transferrin pathway. (A, B, C) TfR1 was initially localized to UB tips and cap mesenchyme. By E13, renal vesicles also expressed TfR1 (*B, C). TfR1 expression was reduced or absent in glomeruli (“G”), stroma and capsule. (D) Rhodamine- and (E) fluorescein-transferrin endocytosis paralleled TfR1 expression. Stroma and capsule were weakly labeled despite active fluid-phase endocytosis (rhodamine-dextran; E). (*Presumptive distal nephron; Bar= 10 μm).