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. Author manuscript; available in PMC: 2010 Jan 27.
Published in final edited form as: J Am Coll Cardiol. 2009 Jan 27;53(4):345–352. doi: 10.1016/j.jacc.2008.07.072

Table 3.

a: Risk of CHD Events Associated with Increasing Absolute CAC Scores across Age-Gender-Race CAC Percentiles
All CHD Events (n=163)
Un-adjusted HR (95% CI) FRS* Adjusted HR (95% CI)
Age-Gender-Race CAC <75th Percentile (n=1811)
CAC 1-100 (n=1314) 1 (reference group) 1 (reference group)
CAC 101-400 (n=421) 2.77 (1.60-4.77) 2.50 (1.27-4.92)
CAC>400 (n=76) 5.53 (2.52-12.15) 5.58 (2.34-13.33)
Age-Gender-Race CAC 75-90th percentile (n=931)
CAC 1-100 (n=379) 1 (reference group) 1 (reference group)
CAC 101-400 (n= 322) 2.16 (0.98-4.78) 2.33 (0.78-6.96)
CAC>400 (n=230) 2.99 (1.34-6.68) 2.18 (0.65-7.37)
Age-Gender-Race CAC >90th percentile (n=652)
CAC 1-100 (n=100) 1 (reference group) 1 (reference group)
CAC 101-400 (n=183) 7.31 (0.95-56.29) 5.41 (0.68-42.86)
CAC>400 (n=369) 11.22 (1.53-82.19) 5.97 (0.78-47.23)
b: Risk of CHD Events Associated with Age-Gender-Race CAC Percentiles across Increasing Absolute CAC Scores
All CHD Events (n=163)
Un-adjusted HR (95% CI) FRS Adjusted HR (95% CI)
CAC 1-100 (n=1793)
Age-Gender-Race CAC <75th Percentile (n=1314) 1 (reference group) 1 (reference group)
Age-Gender-Race CAC 75-90th percentile (n=379) 1.09 (0.53-2.25) 1.37 (0.47-3.97)
Age-Gender-Race CAC >90th percentile (100) 0.38 (0.05-2.78) 1.07 (0.13-8.65)
CAC 101-400 (n=926)
Age-Gender-Race CAC <75th Percentile (n=421) 1 (reference group) 1 (reference group)
Age-Gender-Race CAC 75-90th percentile (n=322) 0.88 (0.47-1.65) 1.30 (0.62-2.72)
Age-Gender-Race CAC >90th percentile (n=183) 1.08 (0.54-2.16) 2.04 (0.85-4.80)
CAC>400 (n=675)
Age-Gender-Race CAC <75th Percentile (n=76) 1 (reference group) 1 (reference group)
Age-Gender-Race CAC 75-90th percentile (n=230) 0.68 (0.26-1.46) 0.59 (0.24-1.45)
Age-Gender-Race CAC >90th percentile (n=652) 0.86 (0.40-1.86) 0.94 (0.41-2.14)
*

Framingham Risk Score