Figure 5.
Organization of RepC binding sites in pAD1 and putative binding sites in other RepBC-containing plasmids. Vertically lined boxes depict repeats in the orientation shown on the right side of the figure. Horizontally lined boxes depict repeats present in the inverted orientation. Numbers in the boxes depict total number of repeats in the cluster. Boxes without numbers contain only a single repeat. Numbers between the boxes depict the size in nucleotides of non-repetitive spacer regions. pAD1 and pAM373 show two different repeat organizations in related pheromone-responsive E. faecalis plasmids. pX02 encodes a RepBC (type Ic) partition module associated with an inc18-like initiator protein (Tinsley et al. 2004). pTE15 (Lin and Chung 1999) contains the most closely related homolog of pAD1 RepB but does not have the type Ic organization of upstream and downstream repeats. The ParAB locus (par2) of E. coli plasmid pB171 is only distantly related to the pAD1 ParBC partition locus, but also possesses upstream and downstream repeats (Ebersbach and Gerdes 2001).