Table 1.

Cardiac parameters of cynomolgus monkeys

	Female						Male
	N	Mean	SD	CV (%)	r	Reference range	N	Mean	SD	CV (%)	r	Reference range
BW (kg)	118	2.56	0.42	16	—	1.47–3.67	119	3.49	0.71	20	—	1.63–5.36
AO (cm)	107	0.79c	0.10	13	0.50a	0.52–1.07	108	0.84	0.10	12	0.71a	0.58–1.11
AVmax (m/s)	54	0.82	0.12	14	–0.11	0.49–1.15	54	0.79	0.14	18	–0.40a	0.39–1.19
LVET (s)	118	0.19c	0.03	15	0.27	0.12–0.27	119	0.20	0.03	15	0.45a	0.12–0.28
LVPEP (s)	64	0.03	0.01	35	0.07	0.00–0.05	65	0.03	0.01	37	0.23	0.00–0.06
LVPEP/ET	64	0.14	0.04	31	0.09	0.02–0.26	65	0.15	0.04	30	0.21	0.02–0.27
HR (bpm)	117	161.36	28.24	18	0.12	86.52–236.20	119	152.39	28.39	19	–0.22	77.22–227.56
RR (ms)	29	354.83	55.42	16	0.11	184.90–524.76	29	377.75	60.56	16	–0.21	192.05–563.44
EPSS (cm)	118	0.01	0.07	592	0.19	−0.18–0.21	119	0.02	0.15	602	0.03	−0.36–0.41
LA (cm)	107	0.89	0.15	16	0.07	0.51–1.28	108	0.99	0.16	16	0.31	0.55–1.42
LA:AO	107	1.14c	0.19	17	–0.30	0.62–1.66	108	1.18	0.18	16	–0.20a	0.69–1.66
IVSd (cm)	107	0.37b	0.06	16	–0.07	0.21–0.53	108	0.40	0.07	17	0.09	0.22–0.58
LVFWd (cm)	107	0.36	0.05	14	–0.16	0.22–0.50	108	0.39	0.07	17	0.37	0.21–0.57
LVIDd (cm)	118	1.35c	0.16	12	0.29a	0.92–1.77	119	1.50	0.17	12	0.32a	1.05–1.96
LVIDs (cm)	118	0.81	0.14	18	0.28a	0.43–1.19	119	0.92	0.15	16	0.34a	0.52–1.31
FS (%)	118	39.93	7.88	20	–0.08	19.05–60.82	119	39.15	6.05	16	–0.15	23.13–55.17

r, Pearson coefficient of correlation between indicated parameter and body weight.

^aCorrelation between the indicated parameter and body weight is statistically significant (P < 0.05).

^bValue for female monkeys differs significantly (P < 0.05; 1-way ANCOVA of body-weight-adjusted means) from that for males.

^cValue for female monkeys differs significantly (P < 0.01; 1-way ANCOVA of body-weight-adjusted means) from that for males.