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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: Exp Lung Res. 2007 Sep;33(7):357–373. doi: 10.1080/01902140701634827

FIGURE 1.

FIGURE 1

Imatinib mesylate reduced hydroxyproline content in crocidolite asbestos-treated mice. Analysis of hydroxyproline levels was used as a measure of collagen deposition. Either 10 mg/kg/day (a) or 50 mg/kg/day (b) of imatinib mesylate was used. TiO2-treated mice were used as an inert particulate control in order to ensure that the changes observed in the lungs of the asbestos-treated mice were not caused by a nonspecific response to particles in the lung. Data are presented as μg/lung of hydroxyproline (mean ± SEM, n = 4 for each group) *P < .05 compared to TiO2-treated control. #P < .05 compared to asbestos-treated mice with empty vector.