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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: Exp Lung Res. 2007 Sep;33(7):357–373. doi: 10.1080/01902140701634827

FIGURE 4.

FIGURE 4

The expression and localization of Abl, PDGFR-α, PDGFR-β, and c-Kit protein tyrosine kinases in human pulmonary fibroblasts. Abl was expressed in the nuclei of primary human IPF fibroblasts (IPF-U.N., IPF-III, IPF-IV, IPF-V). PDGFR-α and PDGFR-β localized to the cell membrane and cytoplasm of normal human pulmonary fibroblasts (CCL-190) and primary human IPF fibroblasts, although PDGFR-β staining was less pronounced. c-Kit was detected in the cytoplasm of normal human pulmonary fibroblasts, but not in the IPF/UIP cell lines. The figure is a representative of all the cell lines, with Abl expression shown in IPF-V, PDGFR-α and PDGFR-β in IPF-III, and c-kit in CCL-190. White color indicates positive staining.

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