Table 2.

Expression ratio of -HSD1 to 11β-HSD2, IGF2 to IGF1, AT1R to AT2R, and ACE1 to ACE2 in LV and RV mRNA

Age (days gestation)	11βHSD1/11βHSD2		IGF2/IGF1		AT1R/AT2R		ACE1/ACE2
	LV	RV	LV	RV	LV	RV	LV	RV
80	62 ± 21	13 ± 3	241 ± 62	978 ± 276	1.4 ± 0.4	4.8 ± 1.6	14 ± 4	2.5 ± 0.2
100	36 ± 11	16 ± 4*f	433 ± 116	949 ± 265	1.7 ± 0.4	1.5 ± 0.3*ag	23 ± 2.8	6.0 ± 0.7*a
120	25 ± 6.4	nm	151 ± 11*b	nm	0.9 ± 0.1	nm	64 ± 6.0*a	nm
130	33 ± 4.5	6.1 ± 1.8	176 ± 25	268 ± 37*ab	1.8 ± 0.4	1.3 ± 0.5*afg	78 ± 31*a	9.6 ± 1.6*a
145	45 ± 5.0	5.7 ± 2.1	88 ± 10*ab	146 ± 48*ab	2.1 ± 0.5	3.3 ± 1.1	212 ± 66*abd	31 ± 6*abd
Postnatal	31 ± 9.0	6.7 ± 0.5	41 ± 7*abcdf	105 ± 4*abd	1.4 ± 0.2	3.8 ± 0.3	133 ± 41*ab	37 ± 6*abd

Ratio of -HSD1 to 11β-HSD2, IGF2 to IGF1, AT1R to AT2R, and ACE1 to ACE2 in left ventricles of 80, 100, 120, 130, and 145 day fetuses and postnatal lambs (pn) and in right ventricles of 80, 100, 130, 145 and postnatal lambs. Ratios were calculated as 2^ˆ−ΔΔCt from mRNA fold changes relative to its counterpart at the same age and are expressed as mean fold change ±SEM. Letters indicate significant differences (p < 0.05) a: vs 80d, b: vs 100d, c: vs120d, d: vs 130d, f: vs 145d, g: vs postnatal lambs; nm, not measured.