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. Author manuscript; available in PMC: 2009 Sep 26.
Published in final edited form as: Vaccine. 2008 Aug 8;26(41):5276–5288. doi: 10.1016/j.vaccine.2008.07.051

Figure 1. SodBFt vaccinated mice exhibit enhanced bacterial clearance following SchuS4 challenge.

Figure 1

(A) C57BL/6 mice were vaccinated i.n. with F. tularensis LVS or sodBFt and challenged with F. tularensis SchuS4 on day 21 post-primary vaccination. At the times indicated, mice were sacrificed and homogenates of the lung, liver, and spleen were plated for determination of bacterial burden. Results shown are the mean ± SEM and are cumulative of two independent experiments conducted (n = 6–8 mice per group). * p < 0.05, ** p < 0.001 using the one-way ANOVA. Ψ All the LVS vaccinated mice died by day 15–17 post-challenge and hence were unavailable for comparisons.