Table 1.

Asymmetric Peroxidation of α,β-unsaturated ketones 1 with 8^a

entry	enone	peroxide	temp(°C)	time(h)	6/3b	yield(%) 6	ee (% )c 6
1d	1A	2a	23	2	91:9	nd	85
2	1A	2a	23	4	92:8	85	91
3	1B	2a	23	4	94:6	88	84
4e	1C	2a	23	4	94:6	91	90
5f	1D	2a	23	4	93:7(95:5)	86(90)	93(90)
6	1E	2a	23	4	90:10	65	91
7	1F	2a	23	4	95:5	90	89
8	1H	2a	23	4	94:6	89	87
9f	1I	2a	23	4	86:14(93:7)	64(77)	94(88)
10	1A	2b	0	16	86:14	74	94
11	1B	2b	0	12	77:23	70	92
12	1C	2b	0	12	88:12	75	92
13	1D	2b	0	16	87:13	77	95
14	1E	2b	0	12	90:10	82	96
15	1F	2b	0	24	89:11	75	94
16	1H	2b	0	24	85:15	66	96
17	1I	2b	0	24	65:35	55	97
18g	1A	2c	0	19	77:23	60	92
19g	1C	2c	0	24	86:14	70	95
20g	1D	2c	0	24	88:12	62	95
21g	1F	2c	0	17	95:5	63	95
22g	1G	2c	0	24	78:22	42	94
23g	1H	2c	0	24	95:5	60	94

^aUnless noted, reactions were run with 0.3 mmol 1, 0.36 mmol 2, see Supporting Information for details.

^bDetermined by ¹H NMR.

^csee Supporting Information for details.

^dReaction was run with 20 mol% TFA in CH2CI2.

^eAbsolute configuration was established as R (see Supporting Inofrmation).

^fThe results in paretheses were obtained with QD-NH₂.

^gReaction was run with 20 mol% TFA.