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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: Nat Med. 2004 Sep 19;10(10):1117–1121. doi: 10.1038/nm1110

Figure 2.

Figure 2

Sensitivity of long-term projections of MDRTB epidemics to the relative fitness of MDR strains. Colored traces represent infection and disease with the MDR strains; black traces represent infection and disease with the drug-sensitive strain. Colors represents the projected course of the epidemic given an assumption about the relative fitness of the ‘fit’ MDR strain (red: cF = −0.2; orange: cF = −0.1; green: cF = 0; blue: cF = 0.1; pink: cF = 0.2). (a) Proportion of population with latent TB infections over time. (b) Prevalence of infectious TB over time. (c) Evolution of mean fitness of extant MDR strains toward the relative fitness of the ‘fit’ MDR strain.