Table 6 Array CGH findings in 11 carriers of reciprocal translocations associated with phenotypic abnormalities*.
Patient (total no of breakpoints before and after array CGH) | Deleted regions | Non‐deleted probe (Mb) | Deletion start (Mb) | Deletion end (Mb) | Non‐ deleted probe (Mb) | Deletion size (Mb) |
---|---|---|---|---|---|---|
1 (2,3) | Del(7q22.3–q31.1) | 105.5 | 105.9 | 113.7 | 113.8 | 7.8 |
2 (2,3) | Del(1q24) | 160.6 | 160.8 | 165.8 | 165.9 | 4.9 |
3 (2,3) | Del(2)(q33.1) | 199.84 | 199.90 | 203.15 | 203.16 | 3.2 |
4 (2,3) | Del(2)(q22.3–q23.1) | 148.14 | 148.18 | 149.32 | 149.33 | 1.1 |
5 (2,4) | Del(6)(q14.3–15) | 85.28 | 86.38 | 90.56 | 90.59 | 4.2 |
6 (2,4) | Del(2)(p22.3–p21) | 33.56 | 33.61 | 41.97 | 42.32 | 8.4 |
7 (2,8) | Del(2)(q23.3–q24.1) | 152.52 | 152.55 | 157.12 | 157.17 | 4.6 |
Del(2)(q31.1) | 175.8 | 175.87 | 177.02 | 177.08 | 1.7 | |
Del(9)(pter–p24.2) | 2.90 | 3.19 | 3.2 | |||
8 (2,4) | Del(6)(q12) | 65.12 | 65.14 | 67.22 | 67.31 | 2.1 |
Del(7)(pter–p22.3) | 2.37 | 2.38 | 2.4 | |||
9 (2,4) | Del(4)(p15.2) | 27.24 | 27.25 | 27.516 | 27.88 | 0.6 |
10 (2,3) | Del(9)(p23–p22.2) | 13.49 | 13.86 | 17.33 | 17.62 | 3.4 |
11 (2,3) | Del(17)(q24.3) | 65.22 | 65.37 | 66.91 | 67.02 | 1.5 |
*Array CGH resolution was about 100 kb (kit 44BB, Agilent) in all patients except 3, 4 and 8, which were studied at a resolution of about 20 kb (kit 244A, Agilent).
Deletions away from the breakpoints are in italics.
Map positions refer to the Genome Assembly May 2004 (Build 35).