Figure 1. Relationship of IFNγ and IL10 SNPs with mycobacterial antigen induced cytokine secretion.

Whole blood from TB not affected (TBNA) Tuberculin skin test positive donors was stimulated with M. tuberculosis culture filtrate (CF) proteins [5 µg/ml] and supernatants tested at 2 days for IL10 secretion and day 5 for IFNγ secretion using ELISA method as described in material and methods. Results are expressed as pg/ml after deducting secretion in un-stimulated whole blood.