Table 3. Genotype frequencies in healthy controls and different clinical forms of tuberculosis (TB).
| Genotypes | TBNA (188) | TBA (188) | PTB (111) | PMN (19) | PMD (63) | PAD (29) | ETB (67) | DTB (20) | LTB (47) |
| IFN-γ (+874) | |||||||||
| TT | 25 (13.3) | 39 (20.74) | 27 (24.32) | 8 (42.11) | 16 (25.4) | 3 (10.34) | 12 (17.91) | 3 (15.00) | 9 (19.15) |
| TA | 87 (46.28) | 83 (44.15) | 47 (42.34) | 6 (31.58) | 28 (44.44) | 13 (44.83) | 30 (44.78) | 8 (40.00) | 22 (46.80) |
| AA | 76 (40.43) | 66 (35.11) | 37 (33.33) | 5 (26.32) | 19 (30.16) | 13 (44.83) | 25 (37.31) | 9 (45.00) | 16 (34.04) |
| χ2 | 3.86 | 6.05 | 10.69 | 5.58 | 0.30 | 0.87 | 0.29 | 1.28 | |
| Corrected p = | 0.08 | 0.034 | 0.012 | 0.029 | 0.588 | 0.433 | 0.859 | 0.278 | |
| Corrected p = | TBNA TST+ (133) | 0.064 | 0.007 | 0.029 | 0.008 | 0.780 | 0.649 | 0.857 | 0.495 |
| IL-10 (−1082) | |||||||||
| GG | 20 (10.64) | 27(14.36) | 19 (17.12) | 4 (21.05) | 7 (11.1) | 8 (27.59) | 8 (11.94) | 4 (20.00) | 4 (8.51) |
| GA | 136 (72.34) | 132 (70.21) | 71 (63.96) | 11 (57.893) | 46(73.02) | 14 (48.25) | 51 (76.12) | 12 (60.00) | 39 (82.98) |
| AA | 32 (17.02) | 29 (15.43) | 21 (18.92) | 4 (21.05) | 10 (15.89) | 7 (24.14) | 8 (11.94) | 4 (20.00) | 4 (8.51) |
| χ2 | 1.25 | 3.09 | 2.20 | 0.05 | 8.41 | 0.98 | 1.85 | 2.52 | |
| Corrected p = | 0.33 | 0.489 | 0.621 | 0.831 | 0.374 | 0.384 | 0.612 | 0.437 | |
| Corrected p = | TBNA TST+ (133) | 0.435 | 0.767 | 0.945 | 0.867 | 0.341 | 0.330 | 0.582 | 0.357 |
Note: Patient stratification is given in Materials and Methods. N for each group given in brackets. Abbreviations used as in Table 1. Number (frequency) of genotypes is indicated. Pearson chi analysis was carried to determine the significance of differences.
All significant p values are indicated in bold. P approaching significance is given in italics. p<0.05 is considered significant.