Fig. 3.
Processing pro-BNP by corin variants. A. Human pro-BNP was stably expressed in HEK 293 cells. The cells were transfected with plasmids expressing wild-type corin or variants. Conditioned medium was collected and pro-BNP processing was analyzed by immunoprecipitation and Western blotting. B. Pro-ABP processing activity was quantified by densitometric analysis of Western blots. The data represent mean ± S.D. from three independent experiments. **p<0.05 vs. WT. n.s., not statistically significant vs. WT.