. Author manuscript; available in PMC: 2009 Mar 9.

Published in final edited form as: Pac Symp Biocomput. 2005:151–161. doi: 10.1142/9789812702456_0015

Table 1.

Selected highly discriminating terms (including children) for the six subcellular localization derived from the search for location-specific terms in SwissProt

Location	Predictive GO Molecular Function terms
nucleus	GO:0003676 Nucleic acid binding
	GO:0008134 Transcription factor binding
	GO:0030528 Transcription regulator activity

membrane	GO:0004872 Receptor activity
	GO:0015267 Channel/pore class transporter activity
	GO:0008528 Peptide receptor activity, G-protein coupled

extracellular	GO:0005125 Cytokine activity
	GO:0030414 Protease inhibitor activity
	GO:0005201 Extracellular matrix structural constituent

mitochondria	GO:0015078 Hydrogen ion transporter activity
	GO:0004738 Pyruvate dehydrogenase activity
	GO:0003995 Acyl-CoA dehydrogenase activity
	GO:0015290 Electrochemical potential-driven transporter activity

E.R.	GO:0004497 Monooxygenase activity
	GO:0016747 Transferase activity, transferring groups other than amino-acyl groups

Golgi	GO:0016757 Transferase activity, transferring glycosyl groups
	GO:0015923 Mannosidase activity
	GO:0005384 Manganese ion transporter activity