Table 1.
Virus | Position and Sequence | ||||||||||||||||||||
--- CypA Binding Loop --- | |||||||||||||||||||||
80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | |
NL4-3 | W | D | R | L | H | P | V | H | A | G | P | I | A | P | G | Q | M | R | E | P | R |
NRC1 | . | . | . | . | . | . | A | Q | . | . | . | V | . | . | . | . | L | . | . | . | . |
NRC2 | . | . | . | . | . | . | . | . | . | . | . | V | . | . | . | . | . | . | . | . | . |
NRC3-1 | . | . | . | V | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
NRC3-5 | . | . | . | V | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
NRC9 | . | . | . | . | . | . | A | . | . | . | . | V | . | . | . | . | . | . | . | . | . |
NRC10 | . | . | . | . | . | . | A | . | . | . | . | . | . | . | . | . | I | . | . | . | . |
*Numbers indicate the amino acid position in the CA protein. The CypA binding loop is indicated in italics [19]. The amino acid sequence for NL4-3 is given in single letter code. Only amino acids that differ from the NL4-3 sequence are shown for the other viruses.