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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: J Biol Chem. 2006 Sep 18;281(45):34705–34715. doi: 10.1074/jbc.M605738200

FIGURE 1. TNFRs co-localize with lipid rafts in human airway smooth muscle cells.

FIGURE 1

A, lipid rafts were detected by confocal microscopy after labeling human airway smooth muscle cells with CTxB-Alexa 488, which binds to the raft-associated glycosphingolipid GM1. B, TNFRs on the surface of the same cells were labeled with biotin-TNF-α and detected with TRITC-avidin. C, the merged image of A and B revealed considerable co-localization of TNFRs and lipid rafts, which was more clearly seen at higher magnification (D). Scale bar = 0.5 μm (A–C) and 0.1 μm (D).