Skip to main content
. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: J Biol Chem. 2006 Sep 18;281(45):34705–34715. doi: 10.1074/jbc.M605738200

FIGURE 7. TNF-α-induced RhoA activation is dependent on TRADD and RIP but independent of TRAF-2.

FIGURE 7

Human airway smooth muscle cells were transfected with control siRNA or siRNA targeted against either TRADD (A), TRAF-2 (B), or RIP (C ). 72 h after transfection, cells were treated with (+) or without (−) TNF-α (200 ng/ml) for 5 min at 37 °C. Cell extracts were analyzed for the expression of adaptor proteins, phosphorylated IKK and IκB, and for activated RhoA as described in the legend to Fig. 4.