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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: Addiction. 2008 Jun;103(6):990–997. doi: 10.1111/j.1360-0443.2008.02210.x

Table 2.

Results from the base and final Cox proportional hazards models of time to onset of cannabis abuse or dependence.

95% Confidence Interval
Hazard Ratio Lower Upper
Base model
Sexual Abuse 2.01 1.37 2.95
Physical Abuse 1.10 0.73 1.66
Paternal risk group:1
 Group 1 - HGHE 1.92 1.21 3.04
 Group 2 - HGLE 1.52 0.75 3.05
 Group 3 - MGLE 1.19 0.59 2.39
 Group 4 – LGLE 1.00 -- --
Final model
Sexual Abuse 2.16 1.48 3.16
Physical Abuse 0.74 0.50 1.10
Paternal risk group:1
 Group 1 - HGHE 1.40 0.88 2.12
 Group 2 - HGLE 1.10 0.57 2.13
 Group 3 - MGLE 1.01 0.49 2.11
 Group 4 – LGLE 1.00 -- --
Male gender 1.23 0.90 1.69
Alcohol abuse or dependence 3.85 2.77 5.35
Conduct disorder2 at ages <16 years 7.36 4.60 11.79
Conduct disorder2 at ages ≥16 years 1.84 1.17 2.90
1

HGHE: High genetic and low environmental risk; HGLE: High genetic and low environmental risk; MGLE: Medium genetic and low environmental risk; LGLE: Low genetic and low environmental risk

2

Three or more conduct disorder symptoms