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Spermine synthase activity and Spermine levels in the present family
| Sample | SMS Activity | Putresine | Spermine | Spermidine | Spd/Spm |
|---|---|---|---|---|---|
| (pmol/h/mg protein) | (nmol/h/mg protein) | ||||
| Normal control | 500 | 0.51 | 6.81 | 3.54 | 0.52 |
| Mother (I-2) | 750 | 0.87 | 9.18 | 6.11 | 0.67 |
| Patient 1 (II-2) | 4 | 0.15 | 2.54 | 8.82 | 3.47 |
| Patient 2 (II-3) | <1 | 0.18 | 3.26 | 11.12 | 3.41 |
Spd = spermidine, Spm = spermine
