Table 2.
Various Types of Abortions and Estimated PRs Among Childhood Cancer Survivors, Sisters, and a Population Comparison Group, With Sisters As Referent
| Study Group | Spontaneous Abortion (643; DO03)*
|
Induced Abortion (640-642; DO04-06)*
|
Ectopic Pregnancy (631; DO00)*
|
Hydatidiform Mole (631.90, 634.29, 634.60, 634.69, 645.0; DO01)*
|
Other Types (634.61, 645.1, 645.2; DO02)*†
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | % | PR‡ | 95% CI | No. | % | PR‡ | 95% CI | No. | % | PR§ | 95% CI | No. | % | PR§ | 95% CI | No. | % | PR§ | 95% CI | |
| Survivors | 109 | 7.4 | 1.23 | 1.00 to 1.52 | 292 | 19.7 | 1.08 | 0.96 to 1.22 | 17 | 1.1 | 0.9 | 0.5 to 1.5 | 3 | 0.2 | 1.0 | 0.2 to 5.0 | 49 | 3.3 | 0.8 | 0.6 to 1.1 |
| Sisters | 304 | 6.0 | 1 | Referent | 961 | 18.9 | 1 | Referent | 66 | 1.3 | 1 | Referent | 10 | 0.2 | 1 | Referent | 207 | 4.1 | 1 | Referent |
| Population comparisons | 1,718 | 6.1 | 0.98 | 0.87 to 1.11 | 5,505 | 19.7 | 1.07 | 1.01 to 1.14 | 433 | 1.5 | 1.2 | 0.9 to 1.6 | 34 | 0.1 | 0.6 | 0.3 to 1.3 | 967 | 3.5 | 0.8 | 0.7 to 1.0 |
Abbreviation: PR, proportion ratio.
*
Discharge diagnoses were coded according to a modified version of the International Classification of Diseases, eighth revision (ICD-8),15 until 1993, and thereafter to ICD-10.16
†
Primarily nonhydatidiform mole and missed abortion.
‡
Adjusted for age of mother at pregnancy (linear spline) and calendar time (linear).
§
Unadjusted estimate.