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. 2008 Sep 8;26(29):4820–4827. doi: 10.1200/JCO.2007.14.1978

Table 2.

Age-Adjusted Means of Psychosocial and Physiological Measures

Measure No. of Patients
Patients With LMP Tumors
Early-Stage Ovarian Cancer Patients
Advanced-Stage Ovarian Cancer Patients
LMP Early Advanced Mean 95% CI Mean 95% CI Mean 95% CI
CES-D
    Total score 25 26 86 10.40 6.92 to 13.88 13.96 10.61 to 17.31 18.23* 16.38 to 20.09
    Vegetative 25 26 86 4.90 3.28 to 6.54 6.05 4.48 to 7.62 7.83 6.96 to 8.70
    Positive 25 26 86 9.27 8.11 to 10.44 8.46 7.34 to 9.58 6.75* 6.12 to 7.37
    Depressed mood 25 26 86 1.86 0.58 to 3.13 3.46 2.23 to 4.69 3.67§ 3.00 to 4.35
    Interpersonal 25 26 86 0.92 0.42 to 1.42 1.14 0.66 to 1.62 1.59 1.32 to 1.85
IL-6 pg/mL
    Plasma 20 23 72 4.07 2.57 to 6.31 8.13 5.25 to 12.45 14.45 11.48 to 18.62
    Ascites 2 5 50 1169.49 246.60 to 5,546.26 3,854.78 1,442.11 to 10,303.86 3451.43 2,511.88 to 4,709.77
Cortisol, nmol/L
    am 18 12 36 14.15 10.39 to 19.11 17.64 12.00 to 24.58 20.49 15.99 to 24.53
    am +30 17 13 34 19.53 15.41 to 24.78 21.63 16.49 to 28.36 26.58 22.44 to 31.50
    pm 18 13 32 6.30 5.03 to 7.89 6.69 5.11 to 8.77 8.10 6.82 to 9.63
    Night 19 14 34 4.91 3.39 to 7.09 7.24 4.71 to 11.09 6.31 4.75 to 8.30
    AUC 17 10 30 51.06 45.98 to 56.12 54.28 47.52 to 61.03 59.16 55.26 to 63.05

Abbreviations: LMP, low malignant potential; CES-D, Center for Epidemiological Studies-Depression Scale; AUC, area under the curve; ES, effect size.

*

Significantly different from LMP at P ≤ .001, ES = .10.

Significantly different from LMP at P < .01, ES = 0.067.

Significantly different from early stage at P < .05, ES = 0.05.

§

Significantly different from LMP at P < .05, ES = 0.04.

Significantly different from LMP at P ≤ .001, ES = 0.18.

Significantly different from LMP at P < .05, ES = 0.11. All significance levels are Bonferroni adjusted.