Table 2.
Measure | No. of Patients
|
Patients With LMP Tumors
|
Early-Stage Ovarian Cancer Patients
|
Advanced-Stage Ovarian Cancer Patients
|
|||||
---|---|---|---|---|---|---|---|---|---|
LMP | Early | Advanced | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |
CES-D | |||||||||
Total score | 25 | 26 | 86 | 10.40 | 6.92 to 13.88 | 13.96 | 10.61 to 17.31 | 18.23* | 16.38 to 20.09 |
Vegetative | 25 | 26 | 86 | 4.90 | 3.28 to 6.54 | 6.05 | 4.48 to 7.62 | 7.83† | 6.96 to 8.70 |
Positive | 25 | 26 | 86 | 9.27 | 8.11 to 10.44 | 8.46 | 7.34 to 9.58 | 6.75*†‡ | 6.12 to 7.37 |
Depressed mood | 25 | 26 | 86 | 1.86 | 0.58 to 3.13 | 3.46 | 2.23 to 4.69 | 3.67§ | 3.00 to 4.35 |
Interpersonal | 25 | 26 | 86 | 0.92 | 0.42 to 1.42 | 1.14 | 0.66 to 1.62 | 1.59 | 1.32 to 1.85 |
IL-6 pg/mL | |||||||||
Plasma | 20 | 23 | 72 | 4.07 | 2.57 to 6.31 | 8.13 | 5.25 to 12.45 | 14.45‖ | 11.48 to 18.62 |
Ascites | 2 | 5 | 50 | 1169.49 | 246.60 to 5,546.26 | 3,854.78 | 1,442.11 to 10,303.86 | 3451.43 | 2,511.88 to 4,709.77 |
Cortisol, nmol/L | |||||||||
am | 18 | 12 | 36 | 14.15 | 10.39 to 19.11 | 17.64 | 12.00 to 24.58 | 20.49 | 15.99 to 24.53 |
am +30 | 17 | 13 | 34 | 19.53 | 15.41 to 24.78 | 21.63 | 16.49 to 28.36 | 26.58 | 22.44 to 31.50 |
pm | 18 | 13 | 32 | 6.30 | 5.03 to 7.89 | 6.69 | 5.11 to 8.77 | 8.10 | 6.82 to 9.63 |
Night | 19 | 14 | 34 | 4.91 | 3.39 to 7.09 | 7.24 | 4.71 to 11.09 | 6.31 | 4.75 to 8.30 |
AUC | 17 | 10 | 30 | 51.06 | 45.98 to 56.12 | 54.28 | 47.52 to 61.03 | 59.16¶ | 55.26 to 63.05 |
Abbreviations: LMP, low malignant potential; CES-D, Center for Epidemiological Studies-Depression Scale; AUC, area under the curve; ES, effect size.
Significantly different from LMP at P ≤ .001, ES = .10.
Significantly different from LMP at P < .01, ES = 0.067.
Significantly different from early stage at P < .05, ES = 0.05.
Significantly different from LMP at P < .05, ES = 0.04.
Significantly different from LMP at P ≤ .001, ES = 0.18.
Significantly different from LMP at P < .05, ES = 0.11. All significance levels are Bonferroni adjusted.