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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Cancer Res. 2009 Jan 1;69(1):282–291. doi: 10.1158/0008-5472.CAN-08-3274

Figure 5. Methylation status of CpG islands classified by SUPER-PatMAn as MP or MR in primary lung tumors.

Figure 5

The methylation status of predicted MP and predicted MR CpG islands was assessed by MSP in a panel of 5 paired normal and cancerous primary lung samples. CpG islands exhibiting hypermethylation in this sample set were further tested in 15 additional normal-tumor (N-T) pairs. A, Representative MSP data for 3 predicted MP CpG islands (ERG, PP2447, SIM2) and 3 predicted MR CpG islands (TPST2, C21orf33, CRYZL1/ITSN1) in 5 N-T pairs. U, unmethylated; M, methylated. B, Summary of methylation frequencies of all CpG islands tested.