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. 2009 Jan 14;15(2):211–218. doi: 10.3748/wjg.15.211

Table 3.

Statistical analysis for several cytokine gene polymorphisms according to high gastric cancer incidence rate and gastric cancer in H pylori-positive Costa Rican patients

High GCIR
Gastric cancer
Pos/Neg OR (95% CI) P-value Pos/Neg OR (95% CI) P-value
Interleukin-1β-511
T/T 28/19 1.9 (0.8-4.3) 0.136 18/47 1.6 (0.7-4.1) 0.283
T/C 50/43 1.4 (0.7-2.8) 0.317 24/93 1.2 (0.5-2.9) 0.629
C/C 23/28 1.0 reference 10/51 1.0 reference
Interleukin-1β+3954
T/T 2/0 - - - 0/2 -
T/C 56/45 1.4 (0.8-2.6) 0.237 39/101 2.1 (1.0-4.3) 0.049
C/C 43/45 1.0 reference 13/88 1.0 reference
Interleukin-1RN intron 2
*2/*2 20/11 2.2 (0.9-5.2) 0.078 4/31 0.7 (0.2-2.2) 0.494
*2/L 31/28 1.2 (0.6-2.3) 0.592 33/59 3.5 (1.7-7.3) 0.001
L/L 50/51 1.0 reference 15/101 1.0 reference
Interleukin-10-1082
A/A 52/49 1.3 (0.3-6.1) 0.766 35/101 3.2 (0.3-30.2) 0.304
G/A 46/37 1.6 (0.3-7.8) 0.551 16/83 1.8 (0.2-17.1) 0.617
G/G 3/4 1.0 reference 1/7 1.0 reference
Interleukin-10-592
A/A 11/12 0.7 (0.3-1.7) 0.406 10/23 3.1 (1.2-8.2) 0.022
C/A 34/31 0.9 (0.5-1.6) 0.668 26/65 3.2 (1.5-6.8) 0.002
C/C 56/47 1.0 reference 16/103 1.0 reference

-: Unable to compute. Pos: Positive; Neg: Negative.