Table 6.
Adjusted odd ratios with 95% confidence intervals and P-value for combinations of host and bacterial factors according to gastric cancer in Costa Rican H pylori-positive patients
Combination of factors |
Gastric Cancer |
||
Pos/Neg | OR (95% CI) | P-value | |
IL-1β+3954_T/C, IL-1RN*2/L, IL-10-592_C/A | |||
Pos | 10/8 | 4.7 (1.7-13.0) | 0.002 |
Neg | 42/183 | ||
IL-1β+3954_T/C, IL-1RN*2/L, IL-10-592_C/A, vacA s1b/m1 | |||
Pos | 9/2 | 7.2 (1.4-36.4) | 0.017 |
Neg | 40/74 | ||
IL-1β+3954_T/C, IL-1RN*2/L, vacA s1b/m1 | |||
Pos | 18/4 | 9.8 (2.9-32.9) | < 0.001 |
Neg | 31/72 | ||
IL-1RN*2/L, IL-10-592_C/A, vacA s1b/m1 | |||
Pos | 14/9 | 3.0 (1.1-8.1) | 0.028 |
Neg | 35/67 | ||
IL-1β+3954_T/C, IL-10-592_C/A, vacA s1b/m1 | |||
Pos | 21/9 | 4.7 (1.9-11.9) | 0.001 |
Neg | 28/67 |