Table 1.

Epidemiology and gene markers of IBD[2–6,48,49]

Epidemiology	Gene markers of IBD
Incidence per 100000	0.5-2.0 (China); 2-14 (North America)
Prevalence per 100000	1-23 (China); 26-246 (North America)
Geography	Northern Countries > Southern Countries; Lower (China)
Age of onset (yr)	20-35 (China)
Sex	M > F (China)
Race	Whites > Blacks; Lower (Chinese)
Possible genetic associations (Chinese)	TNF-308A, CARD15 (NOD2), MIF-173, NAT2, NKG2D, STAT6, CTLA-4, MICA-MICB, HLA-DRB1, HLA class II, IL-18, IL-4, MICA-A5, CD14, TLR4, Fas-670, p53, NF-κB; Chromosome 3, 5, 7, 12, 16 ,19