Table 1.

Gastric lesions at 22 and 28 WPI

Weeks*	H. pylori	Lesion indices, median (range)
		N	D	I	A	H	ED	IM
22	−	9	1.5 (1.5–2)†,‡	1 (0.5–2)‡	2.5 (1.5–3)†,§	2 (1.5–3)§	2 (1.5–2.5)†,‡	3 (2–3)§
22	+	10	3 (2.5–3.5)‡,||	2.5 (2–2.5)‡	3 (3)§,||	3 (2–3)§	3 (3)‡	3.5 (3–3.5)§
28	−	8	2 (1.5–2.5)†,¶	1 (1–1.5)¶	3 (3–3.5)†	2.25 (1.5–3)**	2.75 (2.5–3)†	3 (3–3.5)
28	+	10	3.5 (3–3.5)||, ¶	2.25 (2–2.5)¶	3.5 (3.5)||	3 (3–3.5)**	3 (3)	3.5 (3–3.5)

Abbreviations: D, dysplasia; I, inflammation; A, atrophy; H, hyperplasia; ED, epithelial defects; IM, intestinal metaplasia.

^*Equivalent to WPI.

^†Significant difference between 22 and 28 WPI in uninfected mice, P < 0.05.

^‡Significant difference between uninfected and infected mice at 22 WPI, P < 0.001.

^§Significant difference between uninfected and infected mice at 22 WPI, P < 0.05.

^||Significant difference between 22 and 28 WPI in infected mice, P < 0.05.

^¶Significant difference between uninfected and infected mice at 28 WPI, P < 0.001.

^**Significant difference between uninfected and infected mice at 28 WPI, P < 0.01.