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| Compd. | IC50 (µM) | Compd. | IC50(µM) | ||
|---|---|---|---|---|---|
| FP | SKBr3 | FP | SKBr3 | ||
| 1 | 4.5 | na | 9a | 19.4 | na |
| 2 | 0.70 | 6.5 | 13 | 0.55 | 6.0 |
| 6a | 4.5 | na | 17 | 1.7 | 4.4 |
| 6b | 2.5 | na | 21a | 14.5 | na |
| 6c | 1.3 | 9.7 | 21b | 31.3 | na |
| 6d | 1.8 | >50 | 21c | 19.6 | na |
| 7b | 9.4 | na | 23a | 28.0 | na |
| 7c | 25.0 | na | 23c | 26.0 | na |
| 7d | 9.5 | na | 23g | 27.0 | na |
Mean of 2 independent determinations.
The other compounds which did not show any inhibitory effect up to 50 µM concentration are not shown in this table
na = not tested in SKBr3 cells
