Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Role of proteasome inhibition in the remethylation pathway. A: Proteasome inhibition by PS-341 (PS) markedly decreased BHMT gene expression; B: Real time PCR analysis of BHMT expression; C: Western blot analysis of BHMT level in the liver of rats fed ethanol chronically and the liver of rats given PS-341. Note that the BHMT level was significantly reduced in the liver of rats treated with PS-341; D: Proteasome inhibition caused a decrease in histone methylation.
