Table 1.
Peptide | Sequence | I-TAC bindinga |
---|---|---|
PT-gliadin | 69 | |
4012 | MVRVPVPQLQPQNPSQQHPQ | 98 |
4013 | PQNPSQQHPQEQVPLVQQQQ | 112 |
4014 | EQVPLVQQQQFLGQQQSFPP | 90 |
4015 | FLGQQQSFPPQQPYPQPQPF | 96 |
4016 | QQPYPQPQPFPSQQPYLQLQ | 103 |
4017 | PSQQPYLQLQPFPQPQLPYL | 94 |
4018 | PFPQPQLPYLQPQPFRPQQP | 93 |
4019 | QPQPFRPQQPYPQPQPQYSQ | 99 |
4020 | YPQPQPQYSQPQQPISQQQQ | 112 |
4021 | PQQPISQQQQQQQQQQQQQQ | 86 |
QQQQQQQQQQQQQQQQQQQQ | — | |
4022 | QQQQQQQQQQQQILQQILQQ | 55 |
4023 | QQILQQILQQQLIPCMDVVL | — |
4024 | QLIPCMDVVLQQHNIAHGRS | 116 |
4025 | QQHNIAHGRSQVLQQSTYQL | 106 |
4026 | QVLQQSTYQLLQELCCQHLW | 36 |
4027 | LQELCCQHLWQIPEQSQCQA | 90 |
4028 | QIPEQSQCQAIHNVVHAIIL | 76 |
4029 | IHNVVHAIILHQQQKQQQQP | 93 |
4030 | HQQQKQQQQPSSQVSFQQPL | 126 |
4031 | SSQVSFQQPLQQYPLGQGSF | 100 |
4032 | QQYPLGQGSFRPSQQNPLAQ | 100 |
4033 | RPSQQNPLAQGSVQPQQLPQ | 108 |
4034 | GSVQPQQLPQFEEIRNLALQ | 95 |
4035 | FEEIRNLALQTLPAMCNVYI | 109 |
4036 | TLPAMCNVYIPPYCTIVPFG | 110 |
4037 | PPYCTIVPFGIFGTNYR | 108 |
NOTE. Designed peptides were subjected to a CXCR3 binding assay based on displacement of [125]-radiolabeled CXCR3 ligand I-TAC. In addition to PT-gliadin, 2 of the synthetic peptides were identified to bind to CXCR3 (depicted in bold).
Percentage binding average (n = 2).