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. Author manuscript; available in PMC: 2009 Mar 9.
Published in final edited form as: Gastroenterology. 2008 Mar 21;135(1):194–204.e3. doi: 10.1053/j.gastro.2008.03.023

Table 1.

Synthetic Peptides

Peptide Sequence I-TAC bindinga
PT-gliadin 69
4012 MVRVPVPQLQPQNPSQQHPQ 98
4013 PQNPSQQHPQEQVPLVQQQQ 112
4014 EQVPLVQQQQFLGQQQSFPP 90
4015 FLGQQQSFPPQQPYPQPQPF 96
4016 QQPYPQPQPFPSQQPYLQLQ 103
4017 PSQQPYLQLQPFPQPQLPYL 94
4018 PFPQPQLPYLQPQPFRPQQP 93
4019 QPQPFRPQQPYPQPQPQYSQ 99
4020 YPQPQPQYSQPQQPISQQQQ 112
4021 PQQPISQQQQQQQQQQQQQQ 86
QQQQQQQQQQQQQQQQQQQQ
4022 QQQQQQQQQQQQILQQILQQ 55
4023 QQILQQILQQQLIPCMDVVL
4024 QLIPCMDVVLQQHNIAHGRS 116
4025 QQHNIAHGRSQVLQQSTYQL 106
4026 QVLQQSTYQLLQELCCQHLW 36
4027 LQELCCQHLWQIPEQSQCQA 90
4028 QIPEQSQCQAIHNVVHAIIL 76
4029 IHNVVHAIILHQQQKQQQQP 93
4030 HQQQKQQQQPSSQVSFQQPL 126
4031 SSQVSFQQPLQQYPLGQGSF 100
4032 QQYPLGQGSFRPSQQNPLAQ 100
4033 RPSQQNPLAQGSVQPQQLPQ 108
4034 GSVQPQQLPQFEEIRNLALQ 95
4035 FEEIRNLALQTLPAMCNVYI 109
4036 TLPAMCNVYIPPYCTIVPFG 110
4037 PPYCTIVPFGIFGTNYR 108

NOTE. Designed peptides were subjected to a CXCR3 binding assay based on displacement of [125]-radiolabeled CXCR3 ligand I-TAC. In addition to PT-gliadin, 2 of the synthetic peptides were identified to bind to CXCR3 (depicted in bold).

a

Percentage binding average (n = 2).