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. 2009 Jan 22;9:8. doi: 10.1186/1471-2334-9-8

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Copyright ©2009 Arino et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Required antiviral stockpile and ratio of the total clinical infections. Required stockpile of antiviral drugs (relative to S₀) as a function of the treatment level for (a) R₀= 1.5; and (b) R₀= 2.5. Ratio of the total number of clinical infections to S₀as a function of the treatment level for: (c) R₀= 1.5; and (d) R₀= 2.5. Solid curves correspond to the case where resistance is absent, and dashed curves represent the scenario in which resistant viruses with HTF are present.