Table 2.
ECG-Parameters (15 week old mice)
| Wild type | Eya3-/- | |||
| male | female | male | female | |
| Parameter | n = 8 | n = 9 | n = 10 | n = 9 |
| PQ interval [ms] | 38.6 ± 0.7 | 40.8 ± 0.7 | 41.3 ± 1.6* | 43.6 ± 0.9* |
| P-wave duration [ms] | 20.4 ± 0.6 | 20.4 ± 0.8 | 20.8 ± 0.6 | 21.4 ± 0.3 |
| QRS-complex duration [ms] | 9.6 ± 0.2 | 9.6 ± 0.2 | 10.0 ± 0.2 | 9.8 ± 0.3 |
| QT interval [ms] | 46.2 ± 1.3 | 41.7 ± 0.6 | 45.6 ± 2.1 | 42.7 ± 0.6 |
| QTcorrected [ms] | 40.6 ± 1.4 | 36.5 ± 0.5 | 40.1 ± 1.5 | 38.2 ± 0.7 |
| RR interval [ms] | 130.6 ± 3.8 | 130.9 ± 4.1 | 130.1 ± 4.9 | 125.2 ± 3.7 |
| Heart rate [bpm] | 463.7 ± 13.5 | 463.4 ± 14.2 | 469.1 ± 18.6 | 482.7 ± 13.3 |
| JT interval [ms] | 4.1 ± 0.6 | 3.7 ± 0.1 | 6.0 ± 1.1* | 5.4 ± 0.4* |
| ST interval [ms] | 36.6 ± 1.5 | 32.1 ± 0.6 | 35.6 ± 2.1 | 32.9 ± 0.6 |
| Q amplitude [mV] | 0.01 ± 0.00 | 0.02 ± 0.01 | 0.04 ± 0.01** | 0.03 ± 0.01** |
| R amplitude [mV] | 3.10 ± 0.18 | 3.16 ± 0.35 | 2.32 ± 0.14** | 2.33 ± 0.29** |
| S amplitude [mV] | -1.26 ± 0.22 | -1.03 ± 0.16 | -0.95 ± 0.14 | -1.01 ± 0.16 |
| QRS amplitude [mV] | 4.35 ± 0.17 | 4.19 ± 0.40 | 3.28 ± 0.13*** | 3.34 ± 0.22*** |
*p < 0.05; **p < 0.01; ***p < 0.001 (as compared to the corresponding group of wild-type mice); data are presented as mean ± standard error of the mean