Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Gene Expr Patterns. 2008 Dec 29;9(4):224–230. doi: 10.1016/j.gep.2008.12.005

Fig. 6.

Fig. 6

Bmp7 expression and null phenotype in the female urogenital system at E17.5. (I) Whole mount. (A, B) Schematic depiction of normal (A) and Bmp7 null (B) female urogenital systems. The bladder (bl), Mullerian ducts (MD), urethra (ur), genital tubercle (GT), intestine (in), rectum (r), anus (an), and the cloaca (cl) in the null, are indicated. Dashed lines indicate planes of sections in Fig. 7. (C) X-gal stained Bmp7lacZ/+ female urogenital system, lateral view, and caudal view (insert). Bmp7 expression was present in the Mullerian ducts, the urethra, corpus cavernosum (cc), preputial gland (pg), and the rectum. Bmp7 expression was detected in the oviducts (ov), but not in the ovaries (o). (D, E) Bmp7lacZ/LacZ null female, lateral view (D), caudal view (E). In the null, the rectum adjoins the urethra (E). Cloacal opening is visible beneath the genital tubercle (D, E). LacZ activity was detected in the urethra, rectum, Mullerian ducts, body wall (bw), the mesenchyme of the genital tubercle, and the kidney (k).